Depot injectable biodegradable nanoparticles loaded with recombinant human bone morphogenetic protein-2: preparation, characterization, and in vivo evaluation

OBJECTIVE: The aim of this study is to utilize the biocompatibility characteristics of biodegradable polymers, viz, poly lactide-co-glycolide (PLGA) and polycaprolactone (PCL), to prepare sustained-release injectable nanoparticles (NPs) of bone morphogenetic protein-2 (BMP-2) for the repair of alveo...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Hassan, Ali Habiballah, Hosny, Khaled Mohamed, Murshid, Zuahir A, Alhadlaq, Adel, Alyamani, Ahmed, Naguib, Ghada
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2015
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507488/
https://ncbi.nlm.nih.gov/pubmed/26203226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S79812
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