Enhancement of Sensitivity and Resolution of Surface-Enhanced Laser Desorption/Ionization Time-of-Flight Mass Spectrometric Records for Serum Peptides Using Time-Series Analysis Techniques

BACKGROUND: Measurement of peptide/protein concentrations in biological samples for biomarker discovery commonly uses high-sensitivity mass spectrometers with a surface-processing procedure to concentrate the important peptides. These time-of-flight (TOF) instruments typically have low mass resoluti...

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Publicado no:Clin Chem
Main Authors: Malyarenko, Dariya I., Cooke, William E., Adam, Bao-Ling, Malik, Gunjan, Chen, Haijian, Tracy, Eugene R., Trosset, Michael W., Sasinowski, Maciek, Semmes, O. John, Manos, Dennis M
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507422/
https://ncbi.nlm.nih.gov/pubmed/15550476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1373/clinchem.2004.037283
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