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Myeloid derived suppressor and dendritic cell subsets are related to clinical outcome in prostate cancer patients treated with prostate GVAX and ipilimumab

BACKGROUND: Cancer-related disturbances in myeloid lineage development, marked by high levels of myeloid-derived suppressor cells (MDSC) and impaired dendritic cell (DC) development, are associated with poor clinical outcome due to immune escape and therapy resistance. Redressing this balance may th...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Santegoets, Saskia JAM, Stam, Anita GM, Lougheed, Sinéad M, Gall, Helen, Jooss, Karin, Sacks, Natalie, Hege, Kristen, Lowy, Israel, Scheper, Rik J, Gerritsen, Winald R, van den Eertwegh, Alfons JM, de Gruijl, Tanja D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507359/
https://ncbi.nlm.nih.gov/pubmed/26196012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-014-0031-3
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