iPSC-MSCs Combined with Low-Dose Rapamycin Induced Islet Allograft Tolerance Through Suppressing Th1 and Enhancing Regulatory T-Cell Differentiation

Mesenchymal stem cell (MSC) differentiation is dramatically reduced after long-term in vitro culture, which limits their application. MSCs derived from induced pluripotent stem cells (iPSCs-MSCs) represent a novel source of MSCs. In this study, we investigated the therapeutic effect of iPSC-MSCs on...

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Gepubliceerd in:Stem Cells Dev
Hoofdauteurs: Cheng, Pan-Pan, Liu, Xiao-Cun, Ma, Peng-Fei, Gao, Chang, Li, Jia-Li, Lin, Ying-Ying, Shao, Wei, Han, Shuo, Zhao, Bin, Wang, Lu-Min, Fu, Jia-Zhao, Meng, Lu-Xi, Li, Qing, Lian, Qi-Zhou, Xia, Jun-Jie, Qi, Zhong-Quan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Mary Ann Liebert, Inc. 2015
Onderwerpen:
Original Research Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507355/
https://ncbi.nlm.nih.gov/pubmed/25867817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/scd.2014.0488
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