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Structural asymmetry in a conserved signaling system that regulates division, replication, and virulence of an intracellular pathogen

We have functionally and structurally defined an essential protein phosphorelay that regulates expression of genes required for growth, division, and intracellular survival of the global zoonotic pathogen Brucella abortus. Our study delineates phosphoryl transfer through this molecular pathway, whic...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Willett, Jonathan W., Herrou, Julien, Briegel, Ariane, Rotskoff, Grant, Crosson, Sean
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507200/
https://ncbi.nlm.nih.gov/pubmed/26124143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1503118112
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