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Drug-eluting microarrays to identify effective chemotherapeutic combinations targeting patient-derived cancer stem cells
A new paradigm in oncology establishes a spectrum of tumorigenic potential across the heterogeneous phenotypes within a tumor. The cancer stem cell hypothesis postulates that a minute fraction of cells within a tumor, termed cancer stem cells (CSCs), have a tumor-initiating capacity that propels tum...
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Опубликовано в: : | Proc Natl Acad Sci U S A |
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Главные авторы: | , , , , , , |
Формат: | Artigo |
Язык: | Inglês |
Опубликовано: |
National Academy of Sciences
2015
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Предметы: | |
Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507198/ https://ncbi.nlm.nih.gov/pubmed/26124098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505374112 |
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