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Drug-eluting microarrays to identify effective chemotherapeutic combinations targeting patient-derived cancer stem cells

A new paradigm in oncology establishes a spectrum of tumorigenic potential across the heterogeneous phenotypes within a tumor. The cancer stem cell hypothesis postulates that a minute fraction of cells within a tumor, termed cancer stem cells (CSCs), have a tumor-initiating capacity that propels tum...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Carstens, Matthew R., Fisher, Robert C., Acharya, Abhinav P., Butterworth, Elizabeth A., Scott, Edward, Huang, Emina H., Keselowsky, Benjamin G.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507198/
https://ncbi.nlm.nih.gov/pubmed/26124098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505374112
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