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Aspirin-induced histone acetylation in endothelial cells enhances synthesis of the secreted isoform of netrin-1 thus inhibiting monocyte vascular infiltration

BACKGROUND AND PURPOSE: There are conflicting data regarding whether netrin-1 retards or accelerates atherosclerosis progression, as it can lead either to monocyte repulsion from or retention within plaques depending on its cellular source. We investigated the effect of aspirin, which is widely used...

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Bibliografiske detaljer
Udgivet i:Br J Pharmacol
Main Authors: Passacquale, Gabriella, Phinikaridou, Alkystis, Warboys, Christina, Cooper, Margaret, Lavin, Begona, Alfieri, Alessio, Andia, Marcelo E, Botnar, Rene M, Ferro, Albert
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley & Sons, Ltd 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507159/
https://ncbi.nlm.nih.gov/pubmed/25824964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13144
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