Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma

Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma (NPC), is the first human virus found to encode many miRNAs. However, how these viral miRNAs precisely regulate the tumour metastasis in NPC remains obscure. Here we report that EBV-miR-BART1 is highly expressed in NPC and c...

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Udgivet i:Nat Commun
Main Authors: Cai, Longmei, Ye, Yanfen, Jiang, Qiang, Chen, Yuxiang, Lyu, Xiaoming, Li, Jinbang, Wang, Shuang, Liu, Tengfei, Cai, Hongbing, Yao, Kaitai, Li, Ji-Liang, Li, Xin
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507016/
https://ncbi.nlm.nih.gov/pubmed/26135619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8353
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