Epstein–Barr virus-encoded microRNA BART1 induces tumour metastasis by regulating PTEN-dependent pathways in nasopharyngeal carcinoma

Epstein–Barr virus (EBV), aetiologically linked to nasopharyngeal carcinoma (NPC), is the first human virus found to encode many miRNAs. However, how these viral miRNAs precisely regulate the tumour metastasis in NPC remains obscure. Here we report that EBV-miR-BART1 is highly expressed in NPC and c...

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Enregistré dans:
Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Cai, Longmei, Ye, Yanfen, Jiang, Qiang, Chen, Yuxiang, Lyu, Xiaoming, Li, Jinbang, Wang, Shuang, Liu, Tengfei, Cai, Hongbing, Yao, Kaitai, Li, Ji-Liang, Li, Xin
Format: Artigo
Langue:Inglês
Publié: Nature Pub. Group 2015
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4507016/
https://ncbi.nlm.nih.gov/pubmed/26135619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8353
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