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Bivalent separation into univalents precedes age-related meiosis I errors in oocytes
The frequency of chromosome segregation errors during meiosis I (MI) in oocytes increases with age. The two-hit model suggests that errors are caused by the combination of a first hit that creates susceptible crossover configurations and a second hit comprising an age-related reduction in chromosome...
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| Pubblicato in: | Nat Commun |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Pub. Group
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4507009/ https://ncbi.nlm.nih.gov/pubmed/26130582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8550 |
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