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Chronic NF-κB activation in CD4+ T cells in rheumatoid arthritis is genetically determined by HLA risk alleles
Of identified genetic variants, HLA polymorphisms confer the greatest risk for developing autoimmune diseases, including rheumatoid arthritis (HLA-DRB1*04). There are strong influences of HLA polymorphisms on cell-type specific gene expression in B cells and monocytes. Their influence on gene expres...
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| Yayımlandı: | J Immunol |
|---|---|
| Asıl Yazarlar: | , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2015
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506868/ https://ncbi.nlm.nih.gov/pubmed/26091715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500267 |
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