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Chronic NF-κB activation in CD4+ T cells in rheumatoid arthritis is genetically determined by HLA risk alleles

Of identified genetic variants, HLA polymorphisms confer the greatest risk for developing autoimmune diseases, including rheumatoid arthritis (HLA-DRB1*04). There are strong influences of HLA polymorphisms on cell-type specific gene expression in B cells and monocytes. Their influence on gene expres...

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Detaylı Bibliyografya
Yayımlandı:J Immunol
Asıl Yazarlar: Spurlock, Charles F., Tossberg, John T., Olsen, Nancy J., Aune, Thomas M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506868/
https://ncbi.nlm.nih.gov/pubmed/26091715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500267
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