Neurophysiological Correlates of Central Fatigue in Healthy Subjects and Multiple Sclerosis Patients before and after Treatment with Amantadine

In ten healthy subjects and in ten patients suffering from Multiple Sclerosis (MS), we investigated the cortical functional changes induced by a standard fatiguing repetitive tapping task. The Cortical Silent Period (CSP), an intracortical, mainly GABA(B)-mediated inhibitory phenomenon, was recorded...

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Pubblicato in:Neural Plast
Autori principali: Santarnecchi, Emiliano, Rossi, Simone, Bartalini, Sabina, Cincotta, Massimo, Giovannelli, Fabio, Tatti, Elisa, Ulivelli, Monica
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2015
Soggetti:
Clinical Study
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506817/
https://ncbi.nlm.nih.gov/pubmed/26236509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/616242
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