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C/EBPβ promotes BCR–ABL-mediated myeloid expansion and leukemic stem cell exhaustion

The BCR–ABL fusion oncoprotein accelerates differentiation and proliferation of myeloid cells during the chronic phase of chronic myeloid leukemia (CP-CML). Here, the role of CCAAT/enhancer binding protein β (C/EBPβ), a regulator for ‘emergency granulopoiesis,’ in the pathogenesis of CP-CML was exam...

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Bibliografski detalji
Izdano u:Leukemia
Glavni autori: Hayashi, Y, Hirai, H, Kamio, N, Yao, H, Yoshioka, S, Miura, Y, Ashihara, E, Fujiyama, Y, Tenen, DG, Maekawa, T
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506742/
https://ncbi.nlm.nih.gov/pubmed/22948537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.258
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