C/EBPβ promotes BCR–ABL-mediated myeloid expansion and leukemic stem cell exhaustion

The BCR–ABL fusion oncoprotein accelerates differentiation and proliferation of myeloid cells during the chronic phase of chronic myeloid leukemia (CP-CML). Here, the role of CCAAT/enhancer binding protein β (C/EBPβ), a regulator for ‘emergency granulopoiesis,’ in the pathogenesis of CP-CML was exam...

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Detalhes bibliográficos
Publicado no:Leukemia
Main Authors: Hayashi, Y, Hirai, H, Kamio, N, Yao, H, Yoshioka, S, Miura, Y, Ashihara, E, Fujiyama, Y, Tenen, DG, Maekawa, T
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506742/
https://ncbi.nlm.nih.gov/pubmed/22948537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2012.258
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