Complement-binding Donor-specific Anti-HLA Antibodies and Risk of Primary Graft Failure in Hematopoietic Stem Cell Transplantation

Detection of donor-specific anti-HLA antibodies (DSA) has been associated with graft rejection in all forms of transplantation. The mechanism by which DSA increase the risk of graft failure remains unclear. We hypothesized that complement-binding DSA are associated with engraftment failure in hemato...

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Detalhes bibliográficos
Publicado no:Biol Blood Marrow Transplant
Main Authors: Ciurea, Stefan O., Thall, Peter F., Milton, Denái R., Barnes, Titus H., Kongtim, Piyanuch, Carmazzi, Yudith, López, Asdrúbal A., Yap, Dianne Y., Popat, Uday, Rondon, Gabriela, Lichtiger, Benjamin, Aung, Fleur, Afshar-Kharghan, Vahid, Ma, Qing, Fernández-Viña, Marcelo, Champlin, Richard E., Cao, Kai
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506716/
https://ncbi.nlm.nih.gov/pubmed/25985919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbmt.2015.05.001
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