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Decellularized skeletal muscle as an in vitro model for studying drug-extracellular matrix interactions

Several factors can affect drug absorption after intramuscular (IM) injection: drug solubility, drug transport across cell membranes, and drug metabolism at the injection site. We found that potential interactions between the drug and the extracellular matrix (ECM) at the injection site can also aff...

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Detalhes bibliográficos
Publicado no:Biomaterials
Main Authors: Wassenaar, Jean W., Boss, Gerry R., Christman, Karen L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506649/
https://ncbi.nlm.nih.gov/pubmed/26125502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2015.06.033
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