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Preclinical pharmacology of perampanel, a selective non-competitive AMPA receptor antagonist
Perampanel [2-(2-oxo-1-phenyl-5-pyridin-2-yl-1,2-dihydropyridin-3-yl)benzonitrile; E2007] is a potent, selective, orally-active non-competitive AMPA receptor antagonist developed for the treatment of epilepsy. Perampanel has a 2,3’-bipyridin-6’-one core structure, distinguishing it chemically from o...
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| Publicado no: | Acta Neurol Scand Suppl |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4506647/ https://ncbi.nlm.nih.gov/pubmed/23480152 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ane.12100 |
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