Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

BACKGROUND: Malaria invasion of red blood cells involves multiple parasite-specific targets that are easily accessible to inhibitory compounds, making it an attractive target for antimalarial development. However, no current antimalarial agents act against host cell invasion. RESULTS: Here, we demon...

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Vydáno v:BMC Biol
Hlavní autoři: Wilson, Danny W, Goodman, Christopher D, Sleebs, Brad E, Weiss, Greta E, de Jong, Nienke WM, Angrisano, Fiona, Langer, Christine, Baum, Jake, Crabb, Brendan S, Gilson, Paul R, McFadden, Geoffrey I, Beeson, James G
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506589/
https://ncbi.nlm.nih.gov/pubmed/26187647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0162-0
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