Macrolides rapidly inhibit red blood cell invasion by the human malaria parasite, Plasmodium falciparum

BACKGROUND: Malaria invasion of red blood cells involves multiple parasite-specific targets that are easily accessible to inhibitory compounds, making it an attractive target for antimalarial development. However, no current antimalarial agents act against host cell invasion. RESULTS: Here, we demon...

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Detalhes bibliográficos
Publicado no:BMC Biol
Main Authors: Wilson, Danny W, Goodman, Christopher D, Sleebs, Brad E, Weiss, Greta E, de Jong, Nienke WM, Angrisano, Fiona, Langer, Christine, Baum, Jake, Crabb, Brendan S, Gilson, Paul R, McFadden, Geoffrey I, Beeson, James G
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506589/
https://ncbi.nlm.nih.gov/pubmed/26187647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-015-0162-0
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