STAT3 polymorphism and Helicobacter pylori CagA strains with higher number of EPIYA-C segments independently increase the risk of gastric cancer

BACKGROUND: Because to date there is no available study on STAT3 polymorphism and gastric cancer in Western populations and taking into account that Helicobacter pylori CagA EPIYA-C segment deregulates SHP-2/ERK-JAK/STAT3 pathways, we evaluated whether the two variables are independently associated...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Rocha, Gifone A, Rocha, Andreia MC, Gomes, Adriana D, Faria, César LL, Melo, Fabrício F, Batista, Sérgio A, Fernandes, Viviane C, Almeida, Nathálie BF, Teixeira, Kádima N, Brito, Kátia S, Queiroz, Dulciene Maria Magalhães
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506573/
https://ncbi.nlm.nih.gov/pubmed/26186918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1533-1
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