Genome-wide microRNA screening reveals that the evolutionary conserved miR-9a regulates body growth by targeting sNPFR1/NPYR

MicroRNAs (miRNAs) regulate many physiological processes including body growth. Insulin/IGF signalling is the primary regulator of animal body growth, but the extent to which miRNAs act in insulin-producing cells (IPCs) is unclear. Here we generate a UAS-miRNA library of Drosophila stocks and perfor...

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Udgivet i:Nat Commun
Main Authors: Suh, Yoon Seok, Bhat, Shreelatha, Hong, Seung-Hyun, Shin, Minjung, Bahk, Suhyoung, Cho, Kyung Sang, Kim, Seung-Whan, Lee, Kyu-Sun, Kim, Young-Joon, Jones, Walton D., Yu, Kweon
Format: Artigo
Sprog:Inglês
Udgivet: Nature Pub. Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506552/
https://ncbi.nlm.nih.gov/pubmed/26138755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms8693
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