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Altering cancer transcriptomes using epigenomic inhibitors

BACKGROUND: Due to the hyper-activation of WNT signaling in a variety of cancer types, there has been a strong drive to develop pathway-specific inhibitors with the eventual goal of providing a chemotherapeutic antagonist of WNT signaling to cancer patients. A new category of drugs, called epigeneti...

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Détails bibliographiques
Publié dans:Epigenetics Chromatin
Auteurs principaux: Gaddis, Malaina, Gerrard, Diana, Frietze, Seth, Farnham, Peggy J
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506402/
https://ncbi.nlm.nih.gov/pubmed/26191083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-8-9
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