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State-dependent control of breathing by the retrotrapezoid nucleus

KEY POINTS: This study explores the state dependence of the hypercapnic ventilatory reflex (HCVR). We simulated an instantaneous increase or decrease of central chemoreceptor activity by activating or inhibiting the retrotrapezoid nucleus (RTN) by optogenetics in conscious rats. . During quiet wake...

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Bibliographic Details
Published in:J Physiol
Main Authors: Burke, Peter GR, Kanbar, Roy, Basting, Tyler M, Hodges, Walter M, Viar, Kenneth E, Stornetta, Ruth L, Guyenet, Patrice G
Format: Artigo
Language:Inglês
Published: John Wiley & Sons, Ltd 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4506188/
https://ncbi.nlm.nih.gov/pubmed/25820491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP270053
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