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IL-10 Production in Macrophages Is Regulated by a TLR-Driven CREB-Mediated Mechanism That Is Linked to Genes Involved in Cell Metabolism

IL-10 is produced by macrophages in diverse immune settings and is critical in limiting immune-mediated pathology. In helminth infections, macrophages are an important source of IL-10; however, the molecular mechanism underpinning production of IL-10 by these cells is poorly characterized. In this s...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Sanin, David E., Prendergast, Catriona T., Mountford, Adrian P.
Formato: Artigo
Idioma:Inglês
Publicado em: AAI 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505959/
https://ncbi.nlm.nih.gov/pubmed/26116503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500146
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