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Discs Large Homolog 1 Splice Variants Regulate p38 –Dependent and –Independent Effector Functions in CD8+ T Cells

Functionally diverse CD8+ T cells develop in response to antigenic stimulation with differing capacities to couple TCR engagement to downstream signals and functions. However, mechanisms of diversifying TCR signaling are largely uncharacterized. Here we identified two alternative splice variants of...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Silva, Oscar, Crocetti, Jillian, Humphries, Lisa A., Burkhardt, Janis K., Miceli, M. Carrie
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505885/
https://ncbi.nlm.nih.gov/pubmed/26186728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133353
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