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MAPK feedback encodes a switch and timer for tunable stress adaptation in yeast
Signaling pathways can behave as switches or rheostats, generating binary or graded responses to a given cell stimulus. We evaluated whether a single signaling pathway can simultaneously encode a switch and a rheostat. We found that the kinase Hog1 mediated a bifurcated cellular response: Activation...
Shranjeno v:
| izdano v: | Sci Signal |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505820/ https://ncbi.nlm.nih.gov/pubmed/25587192 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.2005774 |
| Oznake: |
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