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d(G3T4G3) forms an asymmetric diagonally looped dimeric quadruplex with guanosine 5'-syn-syn-anti and 5'-syn-anti-anti N-glycosidic conformations.

The structure formed by the DNA oligonucleotide d(G3T4G3) has been studied by one- and two-dimensional 1H NMR spectroscopy. In NaCl solution, d(G3T4G3), like d(G4T4G4) (Oxy-1.5), forms a dimeric quadruplex with the thymines in loops across the diagonal of the end quartets. Unlike Oxy-1.5, the dimer...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Smith, F W, Lau, F W, Feigon, J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45058/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937991/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10546
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