Comparable Antigenicity and Immunogenicity of Oligomeric Forms of a Novel, Acute HIV-1 Subtype C gp145 Envelope for Use in Preclinical and Clinical Vaccine Research

Eliciting broadly reactive functional antibodies remains a challenge in human immunodeficiency virus type 1 (HIV-1) vaccine development that is complicated by variations in envelope (Env) subtype and structure. The majority of new global HIV-1 infections are subtype C, and novel antigenic properties...

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Pubblicato in:J Virol
Autori principali: Wieczorek, Lindsay, Krebs, Shelly J., Kalyanaraman, Vaniambadi, Whitney, Stephen, Tovanabutra, Sodsai, Moscoso, Carlos G., Sanders-Buell, Eric, Williams, Constance, Slike, Bonnie, Molnar, Sebastian, Dussupt, Vincent, Alam, S. Munir, Chenine, Agnes-Laurence, Tong, Tina, Hill, Edgar L., Liao, Hua-Xin, Hoelscher, Michael, Maboko, Leonard, Zolla-Pazner, Susan, Haynes, Barton F., Pensiero, Michael, McCutchan, Francine, Malek-Salehi, Shawyon, Cheng, R. Holland, Robb, Merlin L., VanCott, Thomas, Michael, Nelson L., Marovich, Mary A., Alving, Carl R., Matyas, Gary R., Rao, Mangala, Polonis, Victoria R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505676/
https://ncbi.nlm.nih.gov/pubmed/25972551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00412-15
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