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Phosphatidylinositol-(4,5)-Bisphosphate Acyl Chains Differentiate Membrane Binding of HIV-1 Gag from That of the Phospholipase Cδ1 Pleckstrin Homology Domain
HIV-1 Gag, which drives virion assembly, interacts with a plasma membrane (PM)-specific phosphoinositide, phosphatidylinositol-(4,5)-bisphosphate [PI(4,5)P(2)]. While cellular acidic phospholipid-binding proteins/domains, such as the PI(4,5)P(2)-specific pleckstrin homology domain of phospholipase C...
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| Udgivet i: | J Virol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505672/ https://ncbi.nlm.nih.gov/pubmed/25995263 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00794-15 |
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