LMP1-Induced Sumoylation Influences the Maintenance of Epstein-Barr Virus Latency through KAP1

As a herpesvirus, Epstein-Barr virus (EBV) establishes a latent infection that can periodically undergo reactivation, resulting in lytic replication and the production of new infectious virus. Latent membrane protein-1 (LMP1), the principal viral oncoprotein, is a latency-associated protein implicat...

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Publicado en:J Virol
Autores principales: Bentz, Gretchen L., Moss, Charles Randall, Whitehurst, Christopher B., Moody, Cary A., Pagano, Joseph S.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Genome Replication and Regulation of Viral Gene Expression
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505653/
https://ncbi.nlm.nih.gov/pubmed/25948750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00711-15
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