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Arsenic Inhibits DNA Mismatch Repair by Promoting EGFR Expression and PCNA Phosphorylation

Both genotoxic and non-genotoxic chemicals can act as carcinogens. However, while genotoxic compounds lead directly to mutations that promote unregulated cell growth, the mechanism by which non-genotoxic carcinogens lead to cellular transformation is poorly understood. Using a model non-genotoxic ca...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Tong, Dan, Ortega, Janice, Kim, Christine, Huang, Jian, Gu, Liya, Li, Guo-Min
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505521/
https://ncbi.nlm.nih.gov/pubmed/25907674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.641399
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