Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression

The cysteine protease cathepsin L (CTSL) is often thought to act as a tumor promoter by enhancing tumor progression and metastasis. This goes along with increased CTSL activity in various tumor entities; however, the mechanisms leading to high CTSL levels are incompletely understood. With the help o...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Autores principales: Tholen, Martina, Wolanski, Julia, Stolze, Britta, Chiabudini, Marco, Gajda, Mieczyslaw, Bronsert, Peter, Stickeler, Elmar, Rospert, Sabine, Reinheckel, Thomas
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
Materias:
Protein Synthesis and Degradation
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505485/
https://ncbi.nlm.nih.gov/pubmed/25957406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.624353
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