Forkhead Box O6 (FoxO6) Depletion Attenuates Hepatic Gluconeogenesis and Protects against Fat-induced Glucose Disorder in Mice

Excessive endogenous glucose production contributes to fasting hyperglycemia in diabetes. FoxO6 is a distinct member of the FoxO subfamily. To elucidate the role of FoxO6 in hepatic gluconeogenesis and assess its contribution to the pathogenesis of fasting hyperglycemia in diabetes, we generated Fox...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Calabuig-Navarro, Virtu, Yamauchi, Jun, Lee, Sojin, Zhang, Ting, Liu, Yun-Zi, Sadlek, Kelsey, Coudriet, Gina M., Piganelli, Jon D., Jiang, Chun-Lei, Miller, Rita, Lowe, Mark, Harashima, Hideyoshi, Dong, H. Henry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Metabolism
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505471/
https://ncbi.nlm.nih.gov/pubmed/25944898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.650994
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