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Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons

During nervous system development, commissural axons cross the midline despite the presence of repellant ligands. In Drosophila, commissural axons avoid premature responsiveness to the midline repellant Slit by expressing the endosomal sorting receptor Commissureless, which reduces surface expressio...

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Foilsithe in:eLife
Main Authors: Evans, Timothy A, Santiago, Celine, Arbeille, Elise, Bashaw, Greg J
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505356/
https://ncbi.nlm.nih.gov/pubmed/26186094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08407
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