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Epithelial-mesenchymal Transition is Associated with Acquired Resistance to 5-Fluorocuracil in HT-29 Colon Cancer Cells

5-Fluorouracil (5-FU) is commonly used for the therapy of colon cancer; however, acquired resistance to 5-FU is a critical barrier to successful treatment and the primary cause of chemotherapy failure. Epithelialmesenchymal transition (EMT) is a process whereby cells undergo alterations in morpholog...

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Detalhes bibliográficos
Publicado no:Toxicol Res
Main Authors: Kim, A-Young, Kwak, Jae-Hwan, Je, Nam Kyung, Lee, Yun-hee, Jung, Young-Suk
Formato: Artigo
Idioma:Inglês
Publicado em: The Korean Society Of Toxicology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505345/
https://ncbi.nlm.nih.gov/pubmed/26191381
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5487/TR.2015.31.2.151
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