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Heteroresistance to Itraconazole Alters the Morphology and Increases the Virulence of Cryptococcus gattii
Cryptococcus gattii is the main etiological agent of cryptococcosis in immunocompetent individuals. The triazole drug itraconazole is one of the antifungals used to treat patients with cryptococcosis. Heteroresistance is an adaptive mechanism to counteract the stress of increasing drug concentration...
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| Publicado no: | Antimicrob Agents Chemother |
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| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4505268/ https://ncbi.nlm.nih.gov/pubmed/26014951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00466-15 |
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