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Bactericidal Effects and Mechanism of Action of Olanexidine Gluconate, a New Antiseptic

Olanexidine gluconate [1-(3,4-dichlorobenzyl)-5-octylbiguanide gluconate] (development code OPB-2045G) is a new monobiguanide compound with bactericidal activity. In this study, we assessed its spectrum of bactericidal activity and mechanism of action. The minimal bactericidal concentrations of the...

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Pubblicato in:Antimicrob Agents Chemother
Autori principali: Hagi, Akifumi, Iwata, Koushi, Nii, Takuya, Nakata, Hikaru, Tsubotani, Yoshie, Inoue, Yasuhide
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505255/
https://ncbi.nlm.nih.gov/pubmed/25987609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05048-14
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