Superior Serum Concentrations with Posaconazole Delayed-Release Tablets Compared to Suspension Formulation in Hematological Malignancies

Posaconazole (PCZ), approved for prophylaxis against invasive fungal disease in high-risk patients, is commercially available orally as a suspension formulation (PCZ-susp) and as a delayed-release tablet (PCZ-tab). We evaluated the serum steady-state concentrations (C(ss)) of PCZ stratified by the a...

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Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Cumpston, Aaron, Caddell, Ryan, Shillingburg, Alexandra, Lu, Xiaoxiao, Wen, Sijin, Hamadani, Mehdi, Craig, Michael, Kanate, Abraham S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Clinical Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505228/
https://ncbi.nlm.nih.gov/pubmed/25987632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00581-15
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