Open-Label Study To Evaluate the Single-Dose Pharmacokinetics, Safety, and Tolerability of Doripenem in Infants Less than 12 Weeks in Chronological Age

Doripenem, a parenteral carbapenem with broad-spectrum activity against aerobic Gram-negative and Gram-positive and anaerobic pathogens, is currently approved for use in adults in the United States and European Union. Single-dose doripenem pharmacokinetics in 52 infants <12 weeks in chronological...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Cirillo, Iolanda, Vaccaro, Nicole, Castaneda-Ruiz, Bibiana, Redman, Rebecca, Cossey, Veerle, Bradley, John S., Allegaert, Karel
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Clinical Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505202/
https://ncbi.nlm.nih.gov/pubmed/26014957
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00485-15
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