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Reevaluation of chloride's regulation of hemoglobin oxygen uptake: the neglected contribution of protein hydration in allosterism.

We have measured hemoglobin oxygen uptake vs. the partial pressure of oxygen, with independently controlled activities of chloride and water. This control is effected by combining different concentrations of NaCl and sucrose in the bathing solution to achieve: (i) water activities were varied and Cl...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Colombo, M F, Rau, D C, Parsegian, V A
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1994
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45052/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7937985/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.22.10517
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