Transcriptome and ultrastructural changes in dystrophic Epidermolysis bullosa resemble skin aging

The aging process of skin has been investigated recently with respect to mitochondrial function and oxidative stress. We have here observed striking phenotypic and clinical similarity between skin aging and recessive dystrophic Epidermolysis bullosa (RDEB), which is caused by recessive mutations in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Aging (Albany NY)
Prif Awduron: Breitenbach, Jenny S., Rinnerthaler, Mark, Trost, Andrea, Weber, Manuela, Klausegger, Alfred, Gruber, Christina, Bruckner, Daniela, Reitsamer, Herbert A., Bauer, Johann W., Breitenbach, Michael
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2015
Pynciau:
Research Paper
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505166/
https://ncbi.nlm.nih.gov/pubmed/26143532
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