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A Nascent Peptide Signal Responsive to Endogenous Levels of Polyamines Acts to Stimulate Regulatory Frameshifting on Antizyme mRNA

The protein antizyme is a negative regulator of cellular polyamine concentrations from yeast to mammals. Synthesis of functional antizyme requires programmed +1 ribosomal frameshifting at the 3′ end of the first of two partially overlapping ORFs. The frameshift is the sensor and effector in an autor...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Yordanova, Martina M., Wu, Cheng, Andreev, Dmitry E., Sachs, Matthew S., Atkins, John F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505036/
https://ncbi.nlm.nih.gov/pubmed/25998126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.647065
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