Epidermal Growth Factor-dependent Activation of the Extracellular Signal-regulated Kinase Pathway by DJ-1 Protein through Its Direct Binding to c-Raf Protein

DJ-1 is an oncogene and also a causative gene for familial Parkinson disease. DJ-1 has various functions, and the oxidative status of cysteine at position 106 (Cys-106) is crucial for determination of the activation level of DJ-1. Although DJ-1 requires activated Ras for its oncogenic activity and a...

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Detaylı Bibliyografya
Yayımlandı:J Biol Chem
Asıl Yazarlar: Takahashi-Niki, Kazuko, Kato-Ose, Izumi, Murata, Hiroaki, Maita, Hiroshi, Iguchi-Ariga, Sanae M. M., Ariga, Hiroyoshi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2015
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505034/
https://ncbi.nlm.nih.gov/pubmed/26048984
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.666271
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