Type 2 Fibroblast Growth Factor Receptor Signaling Preserves Stemness and Prevents Differentiation of Prostate Stem Cells from the Basal Compartment

Prostate stem cells (P-SCs) are capable of giving rise to all three lineages of prostate epithelial cells, which include basal, luminal, and neuroendocrine cells. Two types of P-SCs have been identified in both human and mouse adult prostates based on prostasphere or organoid cultures, cell lineage...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Huang, Yanqing, Hamana, Tomoaki, Liu, Junchen, Wang, Cong, An, Lei, You, Pan, Chang, Julia Y. F., Xu, Jianming, Jin, Chengliu, Zhang, Zhongying, McKeehan, Wallace L., Wang, Fen
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4505024/
https://ncbi.nlm.nih.gov/pubmed/26032417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.661066
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