Long-Term Continuous Suppression With Once-Yearly Histrelin Subcutaneous Implants for the Treatment of Central Precocious Puberty: A Final Report of a Phase 3 Multicenter Trial

CONTEXT AND OBJECTIVE: The histrelin implant has proven to be an effective method of delivering GnRH analog (GnRHa) therapy to children with central precocious puberty (CPP), yet there are limited data available regarding hormonal suppression and auxological changes during an extended course of ther...

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Bibliographic Details
Published in:J Clin Endocrinol Metab
Main Authors: Silverman, Lawrence A., Neely, E. Kirk, Kletter, Gad B., Lewis, Katherine, Chitra, Surya, Terleckyj, Oksana, Eugster, Erica A.
Format: Artigo
Language:Inglês
Published: Endocrine Society 2015
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504932/
https://ncbi.nlm.nih.gov/pubmed/25803268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-3031
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