Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches

OBJECTIVE: The ductular reaction (DR) involves mobilisation of reactive-appearing duct-like cells (RDC) along canals of Hering, and myofibroblastic (MF) differentiation of hepatic stellate cells (HSC) in the space of Disse. Perivascular cells in stem cell niches produce pleiotrophin (PTN) to inactiv...

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發表在:Gut
Main Authors: Michelotti, Gregory A, Tucker, Anikia, Swiderska-Syn, Marzena, Machado, Mariana Verdelho, Choi, Steve S, Kruger, Leandi, Soderblom, Erik, Thompson, J Will, Mayer-Salman, Meredith, Himburg, Heather A, Moylan, Cynthia A, Guy, Cynthia D, Garman, Katherine S, Premont, Richard T, Chute, John P, Diehl, Anna Mae
格式: Artigo
語言:Inglês
出版: BMJ Publishing Group 2016
主題:
Hepatology
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504836/
https://ncbi.nlm.nih.gov/pubmed/25596181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308176
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