Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches

OBJECTIVE: The ductular reaction (DR) involves mobilisation of reactive-appearing duct-like cells (RDC) along canals of Hering, and myofibroblastic (MF) differentiation of hepatic stellate cells (HSC) in the space of Disse. Perivascular cells in stem cell niches produce pleiotrophin (PTN) to inactiv...

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Bibliografske podrobnosti
izdano v:Gut
Main Authors: Michelotti, Gregory A, Tucker, Anikia, Swiderska-Syn, Marzena, Machado, Mariana Verdelho, Choi, Steve S, Kruger, Leandi, Soderblom, Erik, Thompson, J Will, Mayer-Salman, Meredith, Himburg, Heather A, Moylan, Cynthia A, Guy, Cynthia D, Garman, Katherine S, Premont, Richard T, Chute, John P, Diehl, Anna Mae
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2016
Teme:
Hepatology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504836/
https://ncbi.nlm.nih.gov/pubmed/25596181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308176
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