Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIV(MAC)/SIV(SM)/HIV-2 Lineage Prior to Integration

HIV-2 and SIV(MAC) are AIDS-causing, zoonotic lentiviruses that jumped to humans and rhesus macaques, respectively, from SIV(SM)-bearing sooty mangabey monkeys. Cross-species transmission events such as these sometimes necessitate virus adaptation to species-specific, host restriction factors such a...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Pizzato, Massimo, McCauley, Sean Matthew, Neagu, Martha R., Pertel, Thomas, Firrito, Claudia, Ziglio, Serena, Dauphin, Ann, Zufferey, Madeleine, Berthoux, Lionel, Luban, Jeremy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504712/
https://ncbi.nlm.nih.gov/pubmed/26181333
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1005050
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