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Lv4 Is a Capsid-Specific Antiviral Activity in Human Blood Cells That Restricts Viruses of the SIVMAC/SIVSM/HIV-2 Lineage Prior to Integration.

HIV-2 and SIVMAC are AIDS-causing, zoonotic lentiviruses that jumped to humans and rhesus macaques, respectively, from SIVSM-bearing sooty mangabey monkeys. Cross-species transmission events such as these sometimes necessitate virus adaptation to species-specific, host restriction factors such as TR...

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Detalhes bibliográficos
Main Authors: Massimo Pizzato, Sean Matthew McCauley, Martha R Neagu, Thomas Pertel, Claudia Firrito, Serena Ziglio, Ann Dauphin, Madeleine Zufferey, Lionel Berthoux, Jeremy Luban
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2015-07-01
Colecção:PLoS Pathogens
Acesso em linha:http://europepmc.org/articles/PMC4504712?pdf=render
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