Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi

BACKGROUND: The proportion of tuberculosis attributable to transmission from close contacts is not well known. Comparison of the genome of strains from index patients and prior contacts allows transmission to be confirmed or excluded. METHODS: In Karonga District, Malawi, all tuberculosis patients a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Glynn, Judith R., Guerra-Assunção, José Afonso, Houben, Rein M. G. J., Sichali, Lifted, Mzembe, Themba, Mwaungulu, Lorrain K., Mwaungulu, J. Nimrod, McNerney, Ruth, Khan, Palwasha, Parkhill, Julian, Crampin, Amelia C., Clark, Taane G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504505/
https://ncbi.nlm.nih.gov/pubmed/26181760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132840
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