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Whole Genome Sequencing Shows a Low Proportion of Tuberculosis Disease Is Attributable to Known Close Contacts in Rural Malawi

BACKGROUND: The proportion of tuberculosis attributable to transmission from close contacts is not well known. Comparison of the genome of strains from index patients and prior contacts allows transmission to be confirmed or excluded. METHODS: In Karonga District, Malawi, all tuberculosis patients a...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Glynn, Judith R., Guerra-Assunção, José Afonso, Houben, Rein M. G. J., Sichali, Lifted, Mzembe, Themba, Mwaungulu, Lorrain K., Mwaungulu, J. Nimrod, McNerney, Ruth, Khan, Palwasha, Parkhill, Julian, Crampin, Amelia C., Clark, Taane G.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504505/
https://ncbi.nlm.nih.gov/pubmed/26181760
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0132840
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