Evidence that Chemical Chaperone 4-Phenylbutyric Acid Binds to Human Serum Albumin at Fatty Acid Binding Sites

Endoplasmic reticulum stress elicits unfolded protein response to counteract the accumulating unfolded protein load inside a cell. The chemical chaperone, 4-Phenylbutyric acid (4-PBA) is a FDA approved drug that alleviates endoplasmic reticulum stress by assisting protein folding. It is found effica...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Roy, Debasish, Kumar, Vinod, James, Joel, Shihabudeen, Mohamed Sham, Kulshrestha, Shweta, Goel, Varun, Thirumurugan, Kavitha
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504500/
https://ncbi.nlm.nih.gov/pubmed/26181488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0133012
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