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The Mediating Effect of Leptin on the Relationship Between Body Weight and Knee Osteoarthritis in Older Adults

OBJECTIVE: Obesity is associated with increased risk of osteoarthritis (OA) of the knee. Emerging evidence suggests that adipokines, substances produced by adipose tissue, may play a role in the development of knee OA. Our aim was to determine whether the inflammatory adipokine, leptin, partially me...

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Detalhes bibliográficos
Publicado no:Arthritis Rheumatol
Main Authors: Fowler-Brown, Angela, Kim, Dae Hyun, Shi, Ling, Marcantonio, Edward, Wee, Christina C., Shmerling, Robert H., Leveille, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504208/
https://ncbi.nlm.nih.gov/pubmed/25302634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.38913
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