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Diet-induced pre-diabetes slows cardiac conductance and promotes arrhythmogenesis

BACKGROUND: Type 2 diabetes is associated with abnormal electrical conduction and sudden cardiac death, but the pathogenic mechanism remains unknown. This study describes electrophysiological alterations in a diet-induced pre-diabetic rat model and examines the underlying mechanism. METHODS: Sprague...

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Détails bibliographiques
Publié dans:Cardiovasc Diabetol
Auteurs principaux: Axelsen, Lene Nygaard, Calloe, Kirstine, Braunstein, Thomas Hartig, Riemann, Mads, Hofgaard, Johannes Pauli, Liang, Bo, Jensen, Christa Funch, Olsen, Kristine Boisen, Bartels, Emil D., Baandrup, Ulrik, Jespersen, Thomas, Nielsen, Lars Bo, Holstein-Rathlou, Niels-Henrik, Nielsen, Morten Schak
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4504126/
https://ncbi.nlm.nih.gov/pubmed/26169175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12933-015-0246-8
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